01:447:480 Topics in Molecular Genetics Subtopic: Evolutionary Developmental Genetics
This course may be used to fulfill the elective requirements of the Biological Sciences major.
Genetics (447:380) or Genetic Analysis (447:384). Developmental Genetics (447:370) recommended.
Evolutionary origins of the vertebrate body plan are major problems in biology. While paleontology and comparative anatomy have revealed the evolutionary trajectories of organs, recent genetics, genomics and developmental biology have been becoming the powerful approaches to answer classical problems. The goal of this course is learning comparative anatomy, developmental mechanisms of organs, and methodologies to integrate genetics, genomics and developmental biology for evolutionary questions through discussion during the course. The training to discover and answer scientific problems in animal diversity will be performed at the American Museum of Natural History.
The main goal of the course is:
- Understand the concept of comparative anatomy and evolutionary history of vertebrate body.
- Understand the evolutionary mechanisms of vertebrate body in the light of genetics and genomics.
- Study state-of-the-art genomics to answer evolutionary questions.
- Learn how to integrate genomics, genetics, and developmental biology to reveal evolutionary. mechanisms.
- Learn how to discover scientific problems from vertebrate morphology on sites.
- Learn how to approach scientific problems and how to discuss scientific ideas.
Course satisfies Departmental Learning Goals
- Knowledge specific goals: Know the terms, concepts and theories in genetics.
- Study basic concepts and terminology of comparative anatomy, developmental biology, and evolutionary genomics.
- Integrate the material from multiple courses and research. That is, to think holistically and to see the whole as well as the parts.
- Learn how to integrate genomics, genetics, and developmental biology to understand vertebrate evolution.
- Discuss methods to approach evolutionary problems based on published scientific papers.
Exams, Assignments, and Grading Policy
Daily mini-quiz and 3 exams. Pre-reading of textbooks and scientific articles before each class is necessary.
20% for pre-class reading – quizzes
15% for a presentation after a field trip to AMNH (an alternative assignment should be arranged in advance with the instructor if a student cannot attend the AMNH trip)
15% for exam I
15% for exam II
15% for final exam
Vertebrates: Comparative Anatomy, Function, Evolution. 7th Edition. by Kenneth Kardon ISBN-13: 978-0078023026
Recommended (but not required)
Developmental Biology 11th Edition by Scott F. Gilbert and Michael J.F. Barresi ISBN-13: 978-0878939787
Other scientific articles that explain evolutionary genomics will be provided via Sakai.
There is no wait list for this course. Please continue to monitor web-reg for openings.
Dr. Tetsuya Nakamura