01:694:492 Gene Regulation in Cancer & Development

Pre- or Corequisites: 01:694:407-408 or 01:447:384-385 or 11:115:403-404 or 11:126:481

Course Description

Gene Regulation in Cancer and Development (01:694:492) is a course for advanced undergraduate students majoring in the Life Sciences.  Molecular biology is an experimental science, and a major goal of this course is to explain not just what molecular biologists know, but how they know it. The course will cover all aspects of gene regulation from transcription to protein modification to explain how 25,000 human genes can make millions of different protein isoforms and mRNA and ncRNA. Mechanisms of molecular clocks and cancer will be covered in terms of gene regulation complexity, feedback loops and rate-limiting steps with emphasis on the methods, experimental design, history, and deductive reasoning that has led to the current state of understanding of these topics.

Syllabus:

Spring 2024 Syllabus (Updated Syllabus will be posted soon)

Course Satisfies MBB Departmental Learning Goals

1. Students should demonstrate an understanding of the knowledge that is needed to begin biomedical research and that is required for post-graduate exams and studies.
2. Students should demonstrate the ability to find and evaluate information about specific biological systems or problems.

Exams, Assignments, and Grading Policy

PowerPoint lecture material and readings for each class will be posted on the relevant Canvas site for this course. Graded assignments in this class consist of three exams, accompanying open-book study guides, two take-home assignments, and in-class participation in active learning activities. 

Course Materials

Course delivery format: In-person only. Lecture slides and select recordings will be made available on Canvas. Exams will be given in-person, in hard copy. 
Textbook: None. All assigned readings from peer reviewed literature will be available in Canvas.

Course Closed?

f this course is closed, please contact This email address is being protected from spambots. You need JavaScript enabled to view it. concerning special permission numbers.

Course Coordinator

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Course Instructors

Prof. Annika Barber (This email address is being protected from spambots. You need JavaScript enabled to view it.)
Prof. Isaac Edery (This email address is being protected from spambots. You need JavaScript enabled to view it.)

Student Support Services

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Rutgers Student Food Pantry: https://ruoffcampus.rutgers.edu/food-pantry

** All information is subject to change at the discretion of the course coordinator.