Course Descriptions

Four modules

• Module 1 – Stem cells, non-neuronal cells in the CNS & Disease
• Instructor: Grumet

1. The origin of the central nervous system (CNS)
2. Cells: Astrocytes, oligodendrocytes, microglia, stem cells
3. Myelin diseases of the CNS (multiple sclerosis & GBS)
4. Brain tumors and stem cells (glioblastoma & medulloblastoma)
5. Delivery of therapies (Stem cells)

• Module 2 – CNS injury
• Instructor: Young

1. Spinal cord injury
2. The responses of neurons and non-neurons to trauma
3. The attempts at repair
4. The impediments to repair
5. The prospects for the future
6. Clinical Trials

• Module 3 –Intracellular mechanisms in neurodegenerative diseases
• Instructor: Cai

1. Organelle transport for normal neuronal function
2. Autophagy-lysosomal regulation in health and diseases
3. Mitochondrial dynamics and quality control in health and diseases
4. ALS, Parkinson’s, Alzheimer’s, and Huntington’s diseases

• Module 4 – Neurotrophins & Adhesion Molecules in Regeneration
• Instructor: Schachner

1. Repellent and attractive cell adhesion molecules
2. Synaptic plasticity
3. CNS & PNS Regeneration
4. Neurotrophins (Alder)
5. Models of Autism Spectrum Disorders (Samuels)
6.