Course Descriptions

Special Topics in Molecular Biology and Biochemistry: Sickle Cell Anemia (SCA) – An Interdisciplinary Disease

This course is intended for Life Science majors or those with a strong background in the Biological Sciences.

This course may be used to fulfill the elective requirements of the Biological Sciences major.

Offered:  Spring 2019  Wed Periods 4, 5 (3:20-6:20 PM) CABM Rm 308. 

Credits:  3

Prerequisites:  General Biology 01:119:115-116, 117. 

Course Description: The goal of the course is to learn about the many aspects of sickle cell disease through guest lectures, lectures by the coordinator, a paper and readings during the course of the class. Early in the semester students will decide on a research topic of mutual interest related to some aspect of SCA. Students will present their findings to the class.  By the end of the semester, students will submit a ten page (minimum) fully referenced term paper on their topic. 


01/23/2019 Get To Know You
01/30/2019 Overview of Sickle Cell        Dr. Abram Gabriel
Due: Required Reading – Introduction and Chapter One
02/06/2019 Epidemiology                     Ms. Sarah Leifer
Due: Required Reading – Chapter Two
02/13/2019 Medications for Sickle Cell   Dr. Richard Drachtman 
Due: Required Reading – Chapter Three and Conclusion
02/20/2019 Sickle Cell Trait                  Dr. Abram Gabriel
02/27/2019 Advocacy                          Ms. Mary LaMar
03/06/2019 Race
03/13/2019 CRISPR
03/20/2019 Spring Recess
03/27/2019 Student Presentations
04/03/2019 Student Presentations
04/10/2019 Student Presentations
04/17/2019 Student Presentations
04/24/2019 Student Presentations
05/01/2019 No Class
05/08/2019 Papers are due by 5 pm

Course URL:  

Course Satisfies Learning Goals

1. Students should demonstrate an understanding of the knowledge that is needed to begin biomedical research and that is required for post-graduate exams and studies.

2. Students should demonstrate the ability to find and evaluate information about specific biological systems or problems.

3. Students should demonstrate the ability to design experiments and critically analyze data.

Exams, Assignments, and Grading Policy:

Grading and Evaluation:

The oral and written papers will be 80% of the grade. There will also be several assignments that students will have over the course of the semester dealing with the readings (15%). Attendance is mandatory (5%).  Unexcused absences will result in lowering of the final grade.

Course Materials:  The required text is “The troubled dream of genetic medicine” by K. Wailoo and S. Pemberton published by Johns Hopkins University Press, Baltimore, 2006. The book is only three chapters and the conclusion. It can be obtained online or as ISBN 0-8018-8326-1.  There will be additional readings posted on Sakai.

Course Closed?  There is no wait list for this course. Please monitor Web-Reg for openings.

Faculty: Prof. Abram Gabriel

** All information is subject to change at the discretion of the course coordinator.