This course may be used to fulfill the elective requirements of the Biological Sciences major.
Genetics 01:447:380 or Genetic Analysis I 01:447:384. Requires departmental permission to register.
This is a foundational graduate course in human genetics, covering classical and non-classical patterns of inheritance, human genome structure and evolution, normal and abnormal processes of gene expression, molecular genetic pathology, laboratory methods for genetic analysis, and research approaches to the study of human genetic disease using humans and model organisms. There will be homework assignments, a midterm and final. The course is cross-listed with 16:681:535 (Graduate Human Genetics); thus, student taking the course will comprise a mixture of senior undergraduates and graduate students.
https://sakai.rutgers.edu (login with your Rutgers NetID)
The goals of this Human Genetics course are to provide students a foundation in the key biological concepts and experimental methodologies of human genetics. Specific course objectives
1.Comprehend and apply knowledge of human genetics as it relates to a variety of topics
including inheritance patterns, population and quantitative genetics, and epigenetics
2. Appreciate a variety of genetic and genomic testing technologies and understand their application and utility, in both research and clinical settings
3. Understand the basis of human variation and disease
4.Understand the utility and limitations of model organism research and how such work leads to advances in the understanding and treatment of human genetic disease
Course Satisfies Departmental Learning Goals
1. Knowledge specific goals: Know the terms, concepts and theories in genetics
2. Integrate the material from multiple courses and research. That is, to think holistically and to see the whole as well as the parts
3. Use genetic information and ideas to critically analyze published research articles in genetics.
4. Be able to communicate scientific research through written papers and verbal presentations.
Exams, Assignments, and Grading Policy
35% Homeworks and quiz grades
25% Midterm Exam
40% Final exam (cumulative)
Human Molecular Genetics, 4th ed. By Tom Strachan and Andrew Read
Dr. Linda Brzustowicz
Life Science Building 231
Dr. Maureen Barr
Life Science Building 324
** All information is subject to change at the discretion of the course coordinator.