Prerequisites:
01:160:307 or (Honors) 01:160:315)
Course Syllabus:
Fall 2024 -Dr. Villegas
Fall 2024 - Dr. Brill
Topics include:
- Amino Acids and Proteins
- DNA
- Hemoglobin
- Enzyme Kinetics
- Membranes
- Signal Transduction
- Metabolism
- Carbohydrates
- Glycolysis
- Citric Acid Cycle
- Mitochondria
- Glycogen
- Fatty Acid Metabolism
- Biosynthesis of Amino Acids and Nucleotides
- DNA Repair and Replication
- RNA Metabolism
- Protein Metabolism
Course URL:
Canvas
Course Satisfies Learning Goals:
1. Students should demonstrate an understanding of the knowledge that is needed to begin biomedical research and that is required for post-graduate exams and studies.
2. Students should demonstrate the ability to find and evaluate information about specific biological systems or problems.
3. Students should demonstrate the ability to design experiments and critically analyze data.
Tentative Lecture Schedule:
Week |
Topic |
Reading |
1 |
Biochemistry, Evolving Science |
Ch. 1 |
Protein Composition & Structure |
Ch. 2 |
|
2 |
Exploring Proteins & Proteomes |
Ch. 3 |
DNA, RNA & Genetic Information |
Ch. 4 |
|
3 |
Exploring Gene, Genomes, Evolution & Bioinformatics |
Ch. 5, 6 |
Ch. 7 |
||
4 |
Enzymes |
Ch. 8 |
Carbohydrates |
Ch. 11 |
|
5 |
Exam 1 |
Ch. 1-5;8 |
Lipids & Membranes |
Ch 12 |
|
6 |
Channels, pumps |
Ch 13 |
Signal Transduction |
Ch. 14 |
|
7 |
Metabolism |
Ch. 15 |
Glycolysis1 |
Ch. 16 |
|
8 |
Gluconeogenesis & regulation |
Ch. 16 |
Exam 2 |
Ch. 9-15 |
|
9 |
**SPRING BREAK** |
|
**SPRING BREAK** |
||
10 |
Citric Acid Cycle |
Ch. 17 |
Electron Transport Chain |
Ch. 18 |
|
11 |
Oxidative Phosphorylation |
Ch. 18 |
Pentose Phosphate Pathway |
Ch. 20 |
|
12 |
Glycogen |
Ch. 21 |
Fatty Acid Metabolism |
Ch. 22 |
|
13 |
Exam 3 |
Ch. 16-18; 20-22 |
Protein Turnover & AA catabolism |
Ch. 23 |
|
14 |
One Carbon Metabolism |
Ch. 24, 25 |
DNA Replication & Repair |
Ch. 28 |
|
15 |
RNA Synthesis and Processing |
Ch. 29 |
Protein Synthesis |
Ch. 30 |
Exams, Assignments, and Grading Policy:
1. Exams (70%): 3 exams will be administered during the semester as well as a non-cumulative 4thexam during the university scheduled final exam period. The exams will consist of multiple choice, fill in the blank, calculation and short answer questions.
2. Quizzes (15%): Quizzes which are meant to be completed alongside lectures.
3. Homework (15%): Homework for each chapter will be graded on completion.
All exams are closed book. All four examinations will be averaged and weighted equally in assigning final grades. In the rare case that you suspect an exam question has not been accurately graded, a request for re-grading will be considered WITHIN ONE WEEK AFTER EXAM PAPERS HAVE BEEN RETURNED. In such cases, the entire exam will be regraded so that points may be added or subtracted as appropriate.
Course Materials
Required:
Biochemistry 10th Ed, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto, Jr., and Lubert Stryer
ISBN10: 1319417485
ISBN 13: 9781319417482
Course Closed?: If the course is closed, contact Dr. Gabriel Villegas
Faculty
Sections 01 and 02: Dr. Gabriel Villegas
Sections 03: Dr. Steven Brill
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** All information is subject to change at the discretion of the course coordinator.