Prerequisites
Prerequisites are Fundamentals of Neurobiology (01:146:245) or Essentials in Cell Biology & Neuroscience (01:146: 295).
Course Description
This course is offered in the Spring semester and is intended primarily for students majoring in Cell Biology & Neuroscience. It counts as an Advanced course towards the CBN major (R10) or a Life Science Elective (R11). Other students with background knowledge in neuroscience can also register for this course.
The opioid epidemic highlights how chronic pain may result in addiction to painkillers. Understanding the fundamental underpinnings of the debilitating sensations of pain and addictive behaviors provides potential therapeutic avenues for treatment and intervention. The course will focus on the molecular, cellular, and neuroanatomical correlates of pain and addiction. The course consists of three modules. The first module will delve into how different ion channels sense temperature, mechanical stimulus, or pain. The second module will cover the neural circuitries that convey, integrate, and combine these percepts. Finally, students will learn the neuroanatomy and circuits that participate in addictive behavior. Students must have a strong background in cell biology or neurobiology.
Topics: This course will address the fundamental neurobiology of pain and addiction. After completing this course, students should have a solid grasp of the following:
- The ion channels and receptors involved in detecting different sensory modalities and pain.
- The neural circuits underlying pain and somatosensation
- Addiction mechanisms, including circuits, neuroanatomy, and behavior
Course Syllabus
Spring 2025 (Formerly 01:146:464 Topics in Cell Biology and Neuroscience: Neurobiology of Pain and Addiction)
Course Site
There will be a Canvas course site.
Course Satisfies Learning Goals
Learning Goals: The learning goals for this course are consistent with the general goals set by the Department of Cell Biology and Neuroscience and the Division of Life Sciences.
1. Obtain factual and conceptual knowledge in the fundamentals of cell biology and development (with a hint of neuroscience) that will provide a strong foundation for success in advanced training and professional careers.
2. Develop an ability to summarize, integrate, and organize information.
3. Use scientific reasoning to evaluate the potential for current research and discoveries to improve our understanding of cell biology and its relevance to human health and our society.
The mission of the Department of Cell Biology and Neurosciences (CBN) is to provide students with a first-rate educational experience in modern biology. Our graduates will have a solid foundation for any career opportunities that build on biology. Furthermore, they will be inspired to become lifelong learners in the ever-evolving world of biological sciences. The overarching goal of CBN is to prepare our students for successful entry into the workforce, whether in a health professions field or a biomedical research area.
Exams, Assignments, and Grading Policy
The three exams will count for 80% of the remaining points. Three quizzes will account for the remaining 20% of the total grade. The exam will be given at the end of each module, and quizzes will be given in the middle of each module. There will not be a cumulative final exam. Attendance will be taken in class, and up to 10% extra credit will be provided.
Course Closed?
If this course is closed, please add your name to request an SPN for the course under the Cell Biology & Neuroscience section of the SPN Request Page. Please note that the system does not notify students unless they can be accommodated in the course. SPNs are distributed throughout the remainder of the semester and through the drop/add period. If you have any questions, please get in touch with the CBN advising via
Faculty
Professor Kelvin Kwan, Ph.D., Email:
Professor Victoria Abraira, Ph.D., Email:
Prof. Santiago Cuesta, Ph.D., Email:
** All information is subject to change at the discretion of the course coordinator.