01:146:447 Clinical Neurobiology

Prerequisites

Fundamentals of Neurobiology 01:146:245 and Fundamentals of Cell and Developmental Biology 01:146:270.

Course Description

This course focuses on development and function of the nervous with an emphasis on diseases and disorders. Classes will focus on:

• Development of the nervous systems and the role of stem cells.
• Spinal cord injury and neurotrauma, and cell transplants.
• CNS disorders and diseases including demyelination, ALS, Parkinson’s Disease, Alzheimer’s Disease, and Huntington’s Disease.
• Retinal degeneration & Phantom limb pain.

Course Syllabus

Fall 2025

Course Satisfies Learning Goals

• Master factual and conceptual knowledge in cell biology and neuroscience that will provide a solid foundation for success in advanced training and professional careers.
• Develop an ability to summarize, integrate and organize information.
• Use scientific reasoning to evaluate the potential for current research and new discoveries to improve our understanding of cell biology and neuroscience and its relevance to human health and to our society.

Exams, Assignments, and Grading Policy

The first three will be taught by Dr. Martin Grumet and will be worth 2/3 of your grade, and the fourth by Dr. David Margolis will be worth 1/3 of your grade. Exams consist of multiple choice and T/F questions. Time is devoted to review before each exam.

Course Materials

Lecture notes: PowerPoint will be posted on Canvas before each lecture, and these are considered as assignments to study.

No required text. Suggested reference texts:

Essential Cell Biology 6th Edition by Bruce Alberts, ISBN 9781324033394, and Neuroscience 6th Edition by Dale Purves, ISBN-13: 978-1605353807 (chapters 1, 22 and 26). These texts have been used for Fundamentals of Cell and Developmental Biology, and Fundamentals of Neuroscience, respectively for these courses and they serve as reference and foundational information for this course.

Course Closed?

If this course is closed, please add your name to the wait list: https://biology.rutgers.edu/biological-sciences/wait-list-sign-up.  If you have any questions, please contact the Division of Life Sciences - Office of Undergraduate Instruction at This email address is being protected from spambots. You need JavaScript enabled to view it..

Faculty

Course Coordinator and Instructor: Dr. Martin Grumet
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

Instructor: David Margolis
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

** All information is subject to change at the discretion of the course coordinator.