01:146:356 Systems Physiology
Spring, Fall, Summer
General Biology 119:115-116 or 119:101-102 AND General Chemistry with lab 160:161-162 or 163-164, and 160:171.
Open to Juniors and Seniors only. College of Pharmacy students may take this course in their Sophomore year. ALL other students must be Juniors or Seniors (no exceptions).
Physiology according to American Physiological Society is the study of life, and how genes, cells, tissues, and organisms function. Physiologists are occupied with research on key physiological concepts of body systems function. The investigation of living systems at many levels includes molecular processes, cell function, and behavior of isolated tissues, organ systems and the whole organism. The physiologists work is not limited to cell and tissue culture and animal experiments but includes research in human subjects.
Physiological studies of normal function provide the basis to understanding abnormal function that occurs in pathological states. Physiologists are always trying to understand the functional body responses to a variety of internal and external environmental challenges.
In this context the systems physiology course is designed to provide students with an understanding of the function and regulation of organ systems and integration of all systems in the human body. In addition, the importance of mechanisms of communication and control/ regulation to integrate all organ systems to maintain the homeostasis will be emphasized.
Course content will include principles of homeostasis, cell physiology, body composition, neural & hormonal control mechanisms, skeletal muscle physiology, cardiovascular, respiratory, digestive and metabolism, renal and endocrine systems. The integrative body responses to exercise and to the effects of physical training will be presented along with their value as diagnostic tools in medicine.
On Sakai Rutgers portal and it will be available on the first day of classes. https://sakai.rutgers.edu/portal
The goal of this course is to develop the student's knowledge and understanding of the organ systems and human body physiology. Students should be able to identify the operational physiological mechanisms of the majority of the body systems and their function. It is also expected that the students understand the unique role of each organ and organ systems in maintaining homeostasis. They should also be able to distinguish between important physiologic concepts such as the steady state, dynamic equilibrium and homeostasis. It is expected that they understand the synchrony of many systems interacting simultaneously ( e.g. neural control of cardio-respiratory response to maintain the heart rate and blood pressure)
The students should be able to compare, contrast and integrate knowledge of the major organ- function and their complexity of the major body-systems.
Exams, Assignments, and Grading Policy
There will be two hourly mid-term exams, plus a comprehensive final exam that will be administered during finals week. The points earned for exams #1 and #2 will each be worth approximately 30% of a student's grade (60% combined), with the final exam worth 40% of the course grade.
A selection of good books to study physiology for this course:
Sherwood, Lauralee. Human Physiology: From Cells to Systems, 8th edition, Brooks/Cole, Cengage Learning, 2013. ISBN-13: 978-1-111-57743-8, ISBN-1-111-57743-9
Sherwood, Lauralee. Human Physiology: From Cells to Systems, 7th edition, Brooks/Cole, Cengage Learning, 2010. ISBN-13: 978-0-495-39184-5, ISBN-10: 0-495-39184-0.
Silverthorn, Dee Unglaub. Human Physiology: An Integrated Approach with Mastering A&P®, 6th edition, Pearson/Benjamin Cummins, 2012, ISBN-13 978-0-321-75007-5, ISBN-10: 0-321-75007-1.
Silverthorn, Dee Unglaub. Human Physiology: An Integrated Approach, 5th edition, Pearson/Benjamin Cummins, 2010, ISBN-13 978-0-321-55980-7, ISBN-10: 0-321-55980-0.
Widmaier, E.P.; Raff, H.; Strang,K.T. Vander's Human Physiology- The Mechanisms of Body Function, 12th edition. Mc Graw Hill, 2011, ISBN-10: 0-073-04962-X, ISBN-13: 978-0-07-304962-5.
Koeppen, B.M. and Stanton B.A., Berne & Levy Physiology, 6th edition., updated edition, 2010, Mosby-Elsevier, ISBN: 978-0-323-07362-2.
W.F. Boron & E.L. Boulpaep, Medical Physiology, 2e Updated Edition, 2nd Edition, Saunders Elsevier, 2012, ISBN-13: 978-1-4377-1753-2, ISBN-10:1437717535.
Students are expected to have a copy of one of these books and to refer to it as a resource for clarification and reinforcement of material relevant to the learning objectives in this course. All listed books will be held on reserve in Rutgers Library. Some of these books should be available at the Rutgers University Bookstores
Dr. Roseli Golfetti
B-124 Nelson Labs
Phone: 732- 445-8242
If this course is closed and if you have completed all of the pre-requisites, please come to or call the Office of Undergraduate Instruction to be placed on the wait list for the course (Nelson B112, Busch Campus, (732) 445-2075). You may also use this page to request a spot on the wait list.