Bacterial Physiology

01:447:498


This course may be used to fulfill the elective requirements of the Biological Sciences major.


 

Offered

Spring

Credits

3

Prerequisites

General Microbiology 447:390

OR

Molecular Biology/Biochemistry 407- 408 and permission of instructor


 

Course Description

This is an upper level course that focuses on bacterial structure and function relationships; integration of metabolic pathways at the level of gene expression & enzymatic activity; and gene regulation. 

Topics include:

Composition of the Bacterial Cell; Growth

DNA, RNA and protein synthesis;

Control of replication at oriC; DNA methylase

Bacterial Genetics; Mutations; DNA repair

Genomic and Proteomic tools

Cell structure and function

Nucleoid; cell wall; cell membranes; capsules

Cell division apparatus

Central Metabolic Pathways; Anapleurotic pathways

Transport; regulation of use of alternative C sources.

Respiratory pathways; aerobic & anaerobic Biosynthesis; feedback regulation

Regulation of gene expression; nitrogen assimilation;

Autotrophy and Photosynthesis

Ribosome Assembly; Protein Trafficking; Protein Degradation ; translational control

Flagella/ Chemotaxis

Global control networks

Stationary phase

Quorum sensing and biofilms

Sporulation

 

Course URL

 

Exams, Assignments, and Grading Policy

Exams I & II -25% each

Open Book Exam III - 30%

Attendance/participation/discussion - (20%)

Course Materials

Recommended Text: "Microbial Physiology 4th ed." (2002)

Authors: Moat, Foster and Spector. Wiley-Liss (pub) NY

Course Closed?

If this course is closed please contact the course instructor concerning special permission numbers.

Faculty

Dr. Ann C. St. John

Nelson Biology Labs, B412

Phone: 445-3986

E-mail: astjohn@biology.rutgers.edu

** All information is subject to change at the discretion of the course coordinator.